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December News!

posted Dec 5, 2017, 4:34 PM by Vrinda Sant   [ updated Dec 20, 2017, 11:15 PM ]
Press Release:
Experimental Drug Blocks Toxic Ion Flow Linked to Alzheimer’s Disease
"The first drug molecule that can regulate memory loss by directly blocking ions from leaking through nerve cell membranes."

A new drug, that stops ion flow in the brain, has been developed to potentially restore brain function and memory in a mouse model of Alzheimer's disease. 

This drug could be used to treat neurodegenerative diseases, such as Alsheimer's, Parkinson's and ALS. 

Read article!

In Situ Spatial Complementation of Aptamer-Mediated Recognition Enables Live-Cell Imaging of Native RNA Transcripts in Real Time

Let's split

An aptamer-initiated fluorescence complementation (AiFC) method was developed for RNA imaging by engineering a green fluorescence protein (GFP)-mimicking turn-on RNA aptamer into two split fragments that could tandemly bind to target mRNA. The use of AiFC enables the non-invasive, high-contrast real-time imaging of endogenous RNA molecules in living mammalian cells.

Multifunctional stimuli responsive polymer-gated iron and gold embedded silica nano golf balls: Nanoshuttles for targeted on-demand theranostics
Targeted therapeutics: Using nanoparticle assemblies as drug carriers 

Magnetic and gold nanoparticles embedded in silica nanospheres (MGNSs) can be used for remotely targeted delivery of therapeutic molecules. The use of a magnetic field could guide MGNSs to specific anatomic locations, in particular hard-to-teach sites in the skeleton, and the use of multifunctional stimuli responsive polymer as a gate controls the drug release.