About Us


 
We focus on:
  • Developing integrated atomic force microscope (AFM) for multiscale and multimodal studies and 
  •  Their application to understand the basis of human diseases & pathologies.
  • Designing Controlled on-demand theranostic delivery
  • Designing Chip-based in vitro in vivo remotely controlled biomarker sensors

We have used AFM-based multi modal imaging and functional mapping to study protein misfolding, cell-cell and cell-surroundings interactions to understand basic biophysical mechanism of physiology and diseases. Our goal is to make AFM a common-place technology for preventive strategies.

We design nanocarriers for controlled delivery of drugs and diagnostic molecules targeted to any part of the body

We design lab-on-chip for personalized global health. Unlike current technology, our chip sesnors use charge based biomarker sensing and wireless transmission. This will allow both, implantable and wearable real-time diagnosis. 






 

Professor Lal

Professor Lal is Professor of Bioengineering, Mechanical Engineering, Material Science & Engineering, and Co-Director of Center for Excellence in Nanomedcine and Engineering at UC San Diego. 
He received his MS and Masters of Philosophy in Physics and Biophysics from JNU in New Delhi and his Ph.D. in Neurobiology from the University of Alabama. After postdoctoral training at Caltech, he was a faculty member at the University of Chicago and the University of California at Santa Barbara. Before accpeting his current position at UCSD, he was a Professor and the Director of the newly established Center of Nanomedicine at the University of Chicago. 
He is a Fellow of AAAS (the American Association for Advancement of Science) and a Fellow of the American Institute of Medical and Biological Engineering (AIMBE). He was a visiting professor at the Chinese Academy of Sciences, Institute for Applied Physics, Shanghai. Before, he was the UTS Invited Professor in Sydney for the Bionanotechnology initiative and a New Zealand Government International Science Scholar.

Professor Lal is an Associate Editor of the Journal Nanomedicine: Nanotechnology, Biology, Medicine. He is the Chairman of American Nanosolutions, LLC, Vessel ANI, Inc, Ampera Life, Inc and is on advisory board of RC Nano LLC and Be Green Packaging LLC. 

Professor Lal served on the NIH Nano study section. In addition to seminal research publications in the field of nanomedicine, he holds several patents based upon AFM cantilever arrays, microfluidics, optoelectronics and nanotubes for medical diagnostics and medical nanodevices, nanoscale fluid behavior and new TIRF, FRET and related optical microscopy.

Recent Announcements

  • December News!

    Press Release: Experimental Drug Blocks Toxic Ion Flow Linked to Alzheimer’s Disease
    http://ucsdnews.ucsd.edu/pressrelease/experimental_drug_block_toxic_ion_flow_linked_to_alzheimers_disease

    Posted by Abhijith Karkisaval Ganapati
  • September News!
    Publications
    • Wang L.*, Jang G.*, Ban D.*, Sant V.*, Seth J., Kazmi S., Patel N., Yang Q., Lee J., Janetanakit W., Wang S., Head B., Glinsky G, Lal R. Multifunctional Stimuli Responsive Polymer-Gated Iron and Gold-Embedded Silica Nano Golf Balls: Nanoshuttles for Targeted On-Demand Theranostics Nature Bone Research 2017 (Accepted) 

    • Hernandez A.M.*, Urbanke H.*, Gillman A.*, Lee J.*, Ryazanov S., Agbemenyah H.Y., Benito E., Jain G., Kaurani L., Grigorian G., Leonov A., Rezaei-Ghaleh N., Wilken P., Arce F.T., Wagner J., Fuhrman M., Caruana M., Camilleri A., Vassallo N., Zweckstetter M., Benz R., Giese A., Schneider A., Korte M.#, Lal R.#, Griesinger C.#, Eichele G.#, Fischer A.# The diphenylpyrazol compound anle138b blocks Abeta channels and rescues disease phenotypes in a mouse model for amyloid pathology. EMBO Molecular Medicine 2017. DOI: 10.15252/emmm.201707825 

    • Wang Z., Luo Y., Xie X., Hu X., Song H., Zhao Y., Shi J., Wang L., Glinsky G., Chen N., Lal R., Fan C. In-situ Spatial Complementation of Aptamer-mediated Recognition Enables Live-cell Imaging of Native RNA Transcripts in Real Time Angewandte Chemie 2017 doi: 10.1002/anie.201707795
    Congratulations to Grace, Deependra, Vrinda, Jay Seth, Sami, Nirav, Qingqing, and Joon for their new publication!
    Posted Dec 9, 2017, 3:45 PM by Vrinda Sant
  • August News!
    Publications

    Song P., Ye D., Zuo X., Li J., Wang J., Liu H., Hwang M. T., Chao J., Su S., Wang L., Shi J., Wang L., Huang W., Lal R., Fan, C. DNA Hydrogel with Aptamer-Toehold Based Recognition, Cloaking and Decloaking of Circulating Tumor Cells for Live Cell Analysis. Nano Lett. 2017. doi: 10.1021/acs.nanolett.7b01006

    Congratulations to Michael for his new publication!!

    Posted Dec 9, 2017, 3:42 PM by Vrinda Sant
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