At the Lal Nano-Bio-Imaging and Devices Laboratory, we have two large thrusts in basic science and enablingtechnology development centered on our expertise in multiscaleimaging and mechanics with atomic force microscope (AFM). In parallel, we specialize in nanosensors and devices, including controlled on-demand theranostic delivery
In the past we have used the AFM-based multi modality imaging and functional mapping to study protein misfolding, cell-cell and cell-surroundings interactions. We also hope to further improve upon AFM design and application. By these efforts our goal is make AFM a common-place technology useful in the study of normal and pathophysiology, formation of preventive strategies, and characterization of therapeutics among other things. Recently we have expanded our capabilities in nanomaterial based carriers for biological applications
Congratulations to Nirav Patel and Srinivasan Ramachandran on their work with "Ion Channel Formation by Tau Protein: Implications for Alzheimer's Disease and Taupathies". It can be found in the journal Biochemistry.
We would like to welcome masters student, Tianyu Liu, Bradford Rippe, and Ritvek Vasan. Tianyu will be working on electrophysiology measurements of amyloid peptides, Bradford and Ritvek will be working on nanoparticle design and synthesis
We also wish Prof. Karla Santa Cruz well as she heads back to her institution at the University of Sonora.
Congratulations to Fernando Arce, Joon Lee, and Alan Gillman for their contributions to a paper recently published with our collaborators Prof Bruce Kagan and Prof. Ruth Nussinov. The paper entitled "Computational Methods for Structural and Functional Studies of Alzheimer's Amyloid Ion Channels" is published in Methods in Molecular Biology and can be found here.