NANO-BIO-IMAGING & DEVICES LABORATORY


About the Lab

At the Lal Nano-Bio-Imaging and Devices Laboratory, we have two large thrusts in basic science and enabling technology development centered on our expertise in multiscale imaging and mechanics  with atomic force microscope (AFM). In parallel, we specialize in nanosensors and devices, including controlled on-demand theranostic delivery.

In the past we have used the AFM-based multi modality imaging and functional mapping to study protein misfolding, cell-cell and cell-surroundings interactions. We also hope to further improve upon AFM design and application. By these efforts our goal is make AFM a common-place technology useful in the study of normal and pathophysiology, formation of preventive strategies, and characterization of therapeutics among other things. Recently we have expanded our capabilities in nanomaterial based carriers for biological applications.

Professor Lal

Professor Lal received his MS and Masters of Philosophy in Physics and Biophysics from JNU in New Delhi and his Ph.D. in Neurobiology from the University of Alabama. After postdoctoral training at Caltech, he was a faculty member at the University of Chicago and the University of California at Santa Barbara. Before assuming his current position at UCSD, he was a Professor and the Director of the newly established Center of Nanomedicine at the University of Chicago.
Professor Lal was the UTS Invited Professor in Sydney for their BioNanotechnology initiative and a New Zealand Government International Science Scholar. Professor Lal is on advisory board of several entrepreneurial companies, including RC Nano LLC and Be Green Packaging LLC. Professor Lal is an Associate Editor of the journal Nanomedicine: Nanotechnology, Biology and Medicine and serves on the NIH Nano study section. In addition to seminal research publications in the field of nanomedicine, Dr Lal holds several patents based upon AFM cantilever arrays, microfluidics, optoelectronics and nanotubes for medical diagnostics and medical nanodevices, nanoscale fluid behavior and new TIRF, FRET and related optical microscopy.

Recent Announcements

  • August News!
    Congratulations to Michael for his new publication!!

    Song P., Ye D., Zuo X., Li J., Wang J., Liu H., Hwang M. T., Chao J., Su S., Wang L., Shi J., Wang L., Huang W., Lal R., Fan, C. DNA Hydrogel with Aptamer-Toehold Based Recognition, Cloaking and Decloaking of Circulating Tumor Cells for Live Cell Analysis. Nano Lett. 2017. doi: 10.1021/acs.nanolett.7b01006
    Posted Aug 3, 2017, 2:52 PM by Joon Lee
  • July News!
    Congratulations to Nirav, Grace, Malvika, Sami, Deependra for their new publication!

    Janetanakit W., Wang L., Santacruz-Gomez K., Landon, P. B., Sud P. L., Patel N., Jang G., Jain M., Yepremyan A., Kazmi S., A., Ban D.K., Zhang F., and Lal R. Gold Embedded Hollow Silica Nano Golf Balls for Imaging and Photothermal Therapy. ACS Appl. Mater. Interfaces 2017. doi: 10.1021/acsami.7b08398
    Posted Aug 3, 2017, 2:51 PM by Joon Lee
  • June News!
    Congratulations to Joon for his new publication!!

    Li, N., Jang, H., Yuan, M., Li, W., Yun, X., Lee, J., Du, Q., Nussinov, R., Hou, J., Lal, R., Zhang, F. Graphite-Templated Amyloid Nanostructures Formed by A Potential Pentapeptide Inhibitor for Alzheimer’s Disease: A Combined Study of Real-Time Atomic Force Microscopy and Molecular Dynamics Simulations. Langmuir 2017. doi: 10.1021/acs.langmuir.7b00414
    Posted Jul 29, 2017, 11:12 AM by Joon Lee
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