Biosensor Chip Detects Single Nucleotide Polymorphism Wirelessly and With Higher Sensitivity
Congratulations to Abhijith Karkisaval for graduating with his master degree!
Experimental Drug Blocks Toxic Ion Flow Linked to Alzheimer’s Disease
"The first drug molecule that can regulate memory loss by directly blocking ions from leaking through nerve cell membranes."
A new drug, that stops ion flow in the brain, has been developed to potentially restore brain function and memory in a mouse model of Alzheimer's disease. This drug could be used to treat neurodegenerative diseases, such as Alsheimer's, Parkinson's and ALS.
In Situ Spatial Complementation of Aptamer-Mediated Recognition Enables Live-Cell Imaging of Native RNA Transcripts in Real Time
An aptamer-initiated fluorescence complementation (AiFC) method was developed for RNA imaging by engineering a green fluorescence protein (GFP)-mimicking turn-on RNA aptamer into two split fragments that could tandemly bind to target mRNA. The use of AiFC enables the non-invasive, high-contrast real-time imaging of endogenous RNA molecules in living mammalian cells.
Multifunctional stimuli responsive polymer-gated iron and gold embedded silica nano golf balls: Nanoshuttles for targeted on-demand theranostics
Targeted therapeutics: Using nanoparticle assemblies as drug carriers
Magnetic and gold nanoparticles embedded in silica nanospheres (MGNSs) can be used for remotely targeted delivery of therapeutic molecules. The use of a magnetic field could guide MGNSs to specific anatomic locations, in particular hard-to-teach sites in the skeleton, and the use of multifunctional stimuli responsive polymer as a gate controls the drug release.