Post date: Dec 6, 2017 12:34:17 AM
Experimental Drug Blocks Toxic Ion Flow Linked to Alzheimer’s Disease
"The first drug molecule that can regulate memory loss by directly blocking ions from leaking through nerve cell membranes."
A new drug, that stops ion flow in the brain, has been developed to potentially restore brain function and memory in a mouse model of Alzheimer's disease.
This drug could be used to treat neurodegenerative diseases, such as Alsheimer's, Parkinson's and ALS.
In Situ Spatial Complementation of Aptamer-Mediated Recognition Enables Live-Cell Imaging of Native RNA Transcripts in Real Time
An aptamer-initiated fluorescence complementation (AiFC) method was developed for RNA imaging by engineering a green fluorescence protein (GFP)-mimicking turn-on RNA aptamer into two split fragments that could tandemly bind to target mRNA. The use of AiFC enables the non-invasive, high-contrast real-time imaging of endogenous RNA molecules in living mammalian cells.
Multifunctional stimuli responsive polymer-gated iron and gold embedded silica nano golf balls: Nanoshuttles for targeted on-demand theranostics
Targeted therapeutics: Using nanoparticle assemblies as drug carriers