We focus on:
- Developing integrated atomic force microscope (AFM) for multiscale and multimodal studies
- Their application to understand the basis of human diseases & pathologies
- Designing Controlled on-demand theranostic delivery
- Designing Chip-based in vitro & in vivo remotely controlled biomarker sensors
We have used AFM-based multi modal imaging and functional mapping to study protein misfolding, cell-cell and cell-surroundings interactions to understand basic biophysical mechanism underlying normal physiology and diseases. Our goal is to make AFM a common-place technology for preventive strategies.
We design nanocarriers for controlled delivery of drugs and diagnostic molecules targeted to any part of the body.
We design lab-on-chip for personalized global health. Unlike current technology, our chip sesnors use charge based biomarker sensing and wireless transmission. This will allow both, implantable and wearable real-time diagnosis.
Professor Lal is Professor of Bioengineering, Mechanical Engineering, Material Science & Engineering, and Co-Director of Center for Excellence in Nanomedcine and Engineering at UC San Diego.
He received his MS and Masters of Philosophy in Physics and Biophysics from JNU in New Delhi and his Ph.D. in Neurobiology from the University of Alabama. After postdoctoral training at Caltech, he was a faculty member at the University of Chicago and the University of California at Santa Barbara. Before accpeting his current position at UCSD, he was a Professor and the Director of the newly established Center of Nanomedicine at the University of Chicago.
He is a Fellow of AAAS (the American Association for Advancement of Science) and a Fellow of the American Institute of Medical and Biological Engineering (AIMBE). He was a visiting professor at the Chinese Academy of Sciences, Institute for Applied Physics, Shanghai. Before, he was the UTS Invited Professor in Sydney for the Bionanotechnology initiative and a New Zealand Government International Science Scholar.
Professor Lal is an Associate Editor of the Journal Nanomedicine: Nanotechnology, Biology, Medicine. He is the Chairman of Vessel ANI, Inc, Ampera Life, Inc and is on advisory board of RC Nano LLC and Be Green Packaging LLC.
Professor Lal served on the NIH Nano study section. In addition to seminal research publications in the field of nanomedicine, he holds several patents based upon AFM cantilever arrays, microfluidics, optoelectronics and nanotubes for medical diagnostics and medical nanodevices, nanoscale fluid behavior and new TIRF, FRET and related optical microscopy.